I test out my vehicle's for this whenever I first get them. On a weekend when I'm bored, I'll put a 5-gallon gas can in the back and drive it till it dies, exactly 5 gallons. On my 05 WK 4.7 , the gas light came on with 30 miles left according to the computer. I continued driving a mix of Highway and city, but mostly Highway. Average speeds, not trying to deviate from my normal driving behavior. When the computer read 0 miles left, I reset the trip odometer. At around 55 miles there was a definite stutter, probably do to turns and the little bit of gas moving away from the pump. At 68 miles, complete power loss, engine died. Did not attempt to restart. Once the 5 gallons of gas was put in I gave it a few minutes to sit and leach some of the fuel down the lines. After maybe 10 minutes, turned the ignition for about 3 or 4 seconds before it fired right up. The nearest gas station wasn't too far away, maybe a few miles. Once I got there, I remember putting in just a pinch over 15 gallons. Let's say close to 15.15 gallons. Back in 2011 when I bought it, it had about 55,000 miles on it (with light engine tick). Now it has about 140k (still has light engine tick, love ya Rikki Tikki Tavi!). No issues with the fuel pump. Although I have run it down to 0 at least forty or fifty Times by now , I do my best to not make a habit of that anymore. (was unemployed student for a year) And agreed with the winter/bad weather driving, don't ever let it get under a half tank. That's just stupid and asking for trouble. My general rule of thumb for Rikki is, if I turn on the ignition and the gas gauge moves a little bit, (woo hoo it wiggled let's go) there's enough gas to get across town! Small town, not big city. About 60,000 people.
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05 WK 4.7 OME HD F150 MLL's, BFG MT 255/75-17. Lots of stickers, lights EVERYWHERE!