What's the application?
Is it a 96 5.2 PCM going into a 96 5.2? Then no.
Just disconnect the battery and throw in the PCM and reconnect the battery. At most you might have to hold a few rpms with the gas pedal while it relearns how to idle. That's it.
It doesn't need to have a matching VIN or any of that...
If it's a performance build then yes, you're going to want to go with SCT for tuning. It's the only choice unless you want to do a full tilt aftermarket EFI system like FAST etc.
( BTW good luck finding an SCT handheld - old ones are sold out, new ones aren't out yet, and everyone under the sun including the tuners like Sean and Ryan are grabbing them like they're going out of style)
Happiness is clear in the cab and 150 over 150.